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Diógenes Santiago Santos Selected Research

Therapeutics

1/2017New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis.
9/2007Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification.
1/2006Molecular models of tryptophan synthase from mycobacterium tuberculosis complexed with inhibitors.

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Diógenes Santiago Santos Research Topics

Disease

23Tuberculosis (Tuberculoses)
03/2018 - 07/2002
5Infections
11/2017 - 08/2012
2Neoplasms (Cancer)
01/2019 - 10/2003
2Purine Nucleoside Phosphorylase Deficiency
01/2005 - 01/2004
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Diarrhea
11/2017
1Alopecia (Baldness)
11/2017
1Cutaneous Leishmaniasis
01/2017
1Cardiotoxicity
03/2016
1Coinfection
01/2013
1Malaria
01/2011
1Communicable Diseases (Infectious Diseases)
01/2006

Drug/Important Bio-Agent (IBA)

6EnzymesIBA
01/2019 - 01/2004
3Fatty Acids (Saturated Fatty Acids)IBA
01/2017 - 01/2011
3Purine-Nucleoside PhosphorylaseIBA
01/2017 - 01/2004
3shikimate kinaseIBA
01/2013 - 07/2002
3shikimateIBA
01/2013 - 12/2004
3Adenosine Diphosphate (ADP)IBA
01/2013 - 12/2004
3Anti-Bacterial Agents (Antibiotics)IBA
09/2007 - 07/2002
2pentacyano(isoniazid)ferrate(II)IBA
11/2017 - 08/2012
2Antitubercular AgentsIBA
11/2017 - 01/2013
2Rifampin (Rifampicin)FDA LinkGeneric
01/2017 - 03/2016
2Isoniazid (Ftivazide)FDA LinkGeneric
01/2017 - 01/2015
2purineIBA
01/2005 - 01/2004
1Thymidine PhosphorylaseIBA
01/2019
1DNA GyraseIBA
03/2018
1NucleosidesIBA
03/2017
1InterferonsIBA
03/2017
1Mefloquine (Lariam)FDA LinkGeneric
08/2016
1oxazolidineIBA
08/2016
1guanosine 5'-monophosphorothioateIBA
12/2015
1Nucleic AcidsIBA
07/2014
1Hydroxyl RadicalIBA
01/2013
1shikimic acid-3-phosphateIBA
01/2013
1Adenosine Triphosphate (ATP)IBA
01/2013
1pentacyano(2- methyl- 5- (pyridin- 4- yl)- 1,3,4- oxadiazole)ferrate(II)IBA
08/2012
1Proteins (Proteins, Gene)FDA Link
08/2009
1SolutionsIBA
09/2008
11-phenyl-3,3-dimethyltriazene (PDT)IBA
09/2008
1Intergenic DNA (Junk DNA)IBA
07/2007
1Type C PhospholipasesIBA
07/2007
1polyethylene glycol 400IBA
04/2006
1Prephenate DehydrataseIBA
04/2006
1DeoxyguanosineIBA
10/2003
1forodesineIBA
10/2003

Therapy/Procedure

3Therapeutics
01/2017 - 01/2006
1Drug Therapy (Chemotherapy)
01/2013